The Endocannabinoid System

Every human and creature has an Endocannabinoid System. This is from head to toe and this is our most important system in sending and receiving information that keeps our bodies alive and functioning.

CBD, which is cannabinoidal oil, will go throughout the Enodocannabinoid system and aid all body parts that need help and repairing. Due to our Endocannabinoidal system being laden with cannabinoidal receptors; CBD is one of the fasting acting natural supplements on the market and why so many find relief in just moments after using CBD.

Endocannabinoid System
The CB1 receptor is found in abundance in the brain. It is expressed in many different areas of the brain and affects many different neurotransmitters, both excitatory and inhibitory ones. In the brain, CB1 receptors play a role in synaptic plasticity, mood and emotions, anxiety, pain, reward, and appetite. But CB1 receptors can also be found in the periphery where they can affect intestinal motility, fertility, the protective response to cardiovascular damage, and obesity-related metabolic pathway.

The CB2 receptor was initially identified in the immune system. It is now known to play a key role in immune function and immune tissues. The identification of CB2 receptors in the brain is a relatively new finding, and the role of CB2 receptors in the brain is much less understood than that of the CB1 receptors. It has been hypothesized that CB2 receptors can also play a role in synaptic plasticity (learning and memory) within the brain.

Other cannabinoid receptors are garnering attention in the scientific community. TRPV1 receptors are particularly noteworthy because of the role they play in pain signaling. Widely expressed in the body, the TRPV1 receptors are thought to underlie the pain relieving effects of cannabinoids.

GPR55 receptors are another type of cannabinoid receptor getting attention. These receptors (along with their cousins GPR18 and GPR119) are found in many of the tissues that are known to respond to cannabinoids.

CBD can also bind to peroxisome proliferator-activated receptors (also known as PPARs). These receptors are found in the nucleus of cell and help to change the expression of specific target genes. All cannabinoids seem to be able to bind to the PPAR-alpha subtype receptor, but CBD is one of the few to bind to the PPAR-gamma subtype receptor.

Pure Essentials has full spectrum CBD, thus providing all the benefits listed above in one bottle. CBD is one of the most effective singular supplements to achieving health, relief, and reversal of damage done overtime. If you want instant relief and an answer to an ailment. Try Pure Essentials CBD and see how fast you too can have results.